ಕೇಂದ್ರೀಯ ಆಯುರ್ವೇದ ಸಂಶೋಧನಾ ಸಂಸ್ಥೆ
केन्द्रीय आयुर्वेद अनुसंधान संस्थान
CENTRAL AYURVEDA RESEARCH INSTITUTE
Centre of Excellance in Madhumeha
Central Council for Research in Ayurvedic Sciences (CCRAS)
Ministry of AYUSH, Govt. of India

Clinical Research :

The clinical section provides medical services on outpatient basis with facilities for free consultations by the experts, basic clinical investigations, Ayurveda medicines, Yoga, Panchakarma, Marma therapy. The section also organises special clinics, outreach programmes and undertakes Clinical Research Projects. Since inception the Clinical Research Unit has served more than 3 lakh patients. The clinical section is a recognised centre for Pharmacovigilance and therefore any adverse drug events and misleading advertisement are monitored and reported regularly.

NABH and NABL certified CARI hospital is well equipped to provide free consultations by Ayurveda, modern medicine and yoga specialists, Tele-consultation, Ayurveda life style guidelines, medicines, laboratory services, Panchakarma, Marma & Yoga therapies to the public. All these services are free for BPL families and nominal central govt. charges are applicable for others. The campus also has the provision for 28 bedded IPD facility.

Intramural Clinical Research Projects (IMCRP) and collaborative studies :

Completed Projects

Clinical evaluation of herbal formulations in the management of Kuposhana (Malnutrition)

Clinical evaluation of herbo-mineral preparations in the management of ARSHA (Haemorrhoids)

Clinical evaluation of Brahmi Vachaghanavati in the management of Manodvega (Anxiety neurosis)

Evaluation of Shamana therapy and Shodana Chikitsa in the management of Tamaka Swasa (Bronchial asthma)

Clinical evaluation of herbal and herbomineral formulations in the management of Vyanabalavaishamya (Hypertension)

A Multicentric Open Clinical Trial on Dhatri Louha in Iron Deficiency Anaemia.

Documentation of Reported Episode of Prevention/Treatment of Vector Born/Infectious Disease of Ayurveda and Siddha

Multicentric Open clinical trial of Rajapravartinivati in Kastarthava (Dysmenorrhea)

Clinical evaluation on the Rasayana effect of Ashwagandhavalehya in apparently healthy elderly persons

Clinical evaluation of VyoshadiGuggulu and Haritaki Churna in the management of Obesity (Sthaulya)

Evaluation of Clinical Efficacy and Safety of Brahma Rasayana in Apparently Healthy Elderly persons

Prospective, randomized, double blind, placebo controlled comparative trial to evaluate quality of life with AYUSH QOL 2C in patients of non Metastatic Breast Cancer as an adjuvant to Chemotherapy

Clinical Trial to Study the effect of Chyavanaprasha on Aging in Apparently Healthy Elderly Subjects

Clinical evaluation of Vatari Guggulu, Maharasnadikwatha and NarayanaTaila in the management of Osteoarthritis knee

Clinical Evaluation of Ashwagandha Churna and PravalaPishti In The Management of Osteopenia / Osteoporosis

Clinical Evaluation of Kanakasava and Trivritachurna in the management of Bronchial Asthma (Tamakaswasa)

Clinical Evaluation of efficacy of Trayodashangaguggulu, Maharasanadi kwatha & Prasarani Taila in the Management of Gridhrasi (Sciatica)

Preparation of hard copies and Transcription of Ayurveda/medical palm leaf manuscripts and rare books from Karnataka

Swasthya Rakshana Programme under Swachh Bharat

Impact assessment on AYUSH Advisory/ AYUSH based preventive measures in COVID-19 situation” through AYUSH Sanjeevani Mobile app

A prospective non-randomized open label controlled interventional study on the effect of Guduchi Ghan Vati/ Sudarshan Ghan Vati as a prophylactic measure among Containment Zone population exposed to COVID 19

Evaluation of Add on Efficacy & Safety of An Ayurvedic Formulation AYUSH PJ -7 in the Management of Dengue Fever & Prevention of its complications – A Double Blind Clinical Study (Belagavi and Kolar Centres)

A systematic review on Safety and Efficacy of Ayurveda interventions for Urolithiasis

Clinical Evaluation of efficacy of Trayodashangaguggulu, Maharasanadi kwatha &PrasaraniTaila in the Management of Gridhrasi (Sciatica)

Clinical Evaluation of AYUSH PE Eye Drops in the Management of Acute Allergic Conjunctivitis

A systematic review on Safety and Efficacy of Ayurveda interventions for Glaucoma

Knowledge, Attitude and Practice towards Ayurvedic medicine use among the Diabetics –a cross sectional study

Preclinical studies of four anti-diabetic formulations of Central Ayurveda Research Institute (CARI) in high fat diet along with low dose of Streptozotocininduced Diabetes in Wistar rats

Evaluation of anti-diabetic efficacy of four selected classical Ayurvedic poly- herbal formulations in Type-2 Diabetes Mellitus-A randomized pilot study

Clinical evaluation of anti-diabetic efficacy of ‘KaphajaPramehahara Yoga, an Ayurveda poly-herbal formulation in Prediabetes-A pilot study

Knowledge, Attitude, and Practice related to Madhumeha (Diabetes)

A Cross-sectional study of Knowledge, Attitude and Practice related to Madhumeha (Diabetes)

Development of a predictive system for diagnosing the risk of Diabetes using machine learning technique

Randomised Placebo controlled prospective Phase II clinical study of an Ayurvedic coded drug AYUSH-D on glycemic control in prediabetic subjects

Randomised Placebo controlled prospective Phase II clinical study of Ayurvedic coded drug AYUSH-D”in the management of type2 Diabtetes mellitus as add on therapy to Metformin

An observational study to document the potential safety issues and prescription trends of selected Rasausadhis

An open label clinical trial to evaluate clinical efficacy and safety of Ayush AGT in Dandruff (Darunaka)

Profiling of Demographic, Health status and Non Communicable Diseases among Schedule Tribe population in selected States across India- a descriptive, cross sectional, Epidemiological study

Effectiveness of Ayurveda based diet and Lifestyle advocacy on health related Quality of life in Schedule Tribe population in India- a Community based, cluster randomized controlled study

A Prospective Community based Study for the evaluation of Dhatri Loha in the Management of Anaemia (Pandu)

A Prospective Community based Study for the evaluation of Yogaraja Guggulu, Ashwagandha Churna & Narayana Taila in the Management of Osteoarthritis Knee (Janugata Sandhivata)

A Prophylactic Community Based Study to Assess the impact of Ayu Raksha Kit in COVID-19 under THCRP and AMHCP-SCSP Project

A prospective community based study for the evaluation of Punarnavadi Mandura in Anemia (Pandu)

Ongoing Projects

Validation and Reliability testing of Diagnostic Methods in Ayurveda

Evaluation of AYUSH GMH in the subjects of mild to moderate non-alcoholic fatty liver disease (NAFLD) - A Double Blind Randomized Control Clinical study

AYUSH Hospital Management Information System (A-HMIS)

Evaluating the Efficacy of Ayurvedic Intervention as Add on to Conventional Treatment and Explore the Interaction of Epigenetics, Neuro/Gut Biomarkers and Neuroimaging in Pediatric ADHD (Attention deficit hyperactivity disorder)

A Collaborative Double Blind Double Dummy Prospective Randomized Controlled Research Project on classical Ayurveda Management versus Methotrexate in Rheumatoid Arthritis (AMRA STUDY)

Clinical Evaluation of Vidanga churna and Vyoshadi Guggulu in the Management of Medoroga (Obesity)

Randomised Placebo Controlled, Double blind clinical trial to evaluate the effect of Trikatu in Subclinical Hypothyroidism

Anthology of Survey Research outcomes from Medico-Ethno Botanical Survey (MEBS)

Clinical Evaluation of Lekhaniya Gana Kashaya and Arogyavardhini Gutika in the management of Medoroga (Obesity)

Efficacy and safety of Ayurveda Formulation 'Trikatu' in Dyslipidemia - A Prospective Randomized Double Blind Pladebo Controlled Trial

A Cross-sectional survey to explore the association of prakriti with diabetic Retinopathy

“Systems Biology approach to delineate molecular signatures of Prakriti in healthy humans”

Ayurveda therapeutic regimen as on Add-on to optimized conventional management of Parkinson’s disease: An RCT for assessment of Clinical, Cortical excitability, Neuroimmune and Autonomic function parameters

Evaluation of Hepatoprotective activity of PTK as an add on therapy in the patients of Tuberculosis on ATT – A Double blind Randomized control clinical study

Comparative evaluation of field and hydroponic cultivation of selected Ayurvedic medicinal plants

Study of seasonal variation on bioactive compounds of Panchavalkal - 05 medicinal plants used in Ayurveda

Formulation and product development of Ayurveda recipes and nutritional evaluation of selected products

A Multi Centre study to assess the treatment adherence and tolerability of Ayush SR in Generalized Anxiety Disorder

Documentation of traditional Food Recipes of Karnataka and their Validation with Ayurveda and Nutritional perspective

Centre of Excellence for Research & Clinical Services in Madhumeha (Diabetes Mellitus)

National Pharmacovigilance Programme

SERVICES ACTIVITIES SCHEDULE :

Inculcating healthy lifestyle practices in children as per principles of Ayurveda. Lectures, IEC materials, group discussions on health ,hygiene and cleanliness essay competition Fortnightly.

Nutritional supplements as per the concept of Ayurveda to the children at CCI Tab Krimimudgara Rasa, Chyavanaprasha, Drakshamalaka Lehya, Aravindasava fortnightly.

Periodically health checkup for the identification of MAM/SAM children, anemia and their management Measurement of height, weight, mid arm circumference, Hb % and IAP grading as required monthly.

Development of Poshan Vatika at CCI as per feasibility. Plantation of nutritional plants Once during the program.

Research Projects to be initiated :

Evaluation of bioavailability of four Ayurvedic poly-herbal formulations in healthy volunteers – A Crossover Randomized Clinical Trial

A pilot study to evaluate the role of Yoga capsule as add-on in reducing Serum Glucose levels in diabetes.

Outreach programmes :

Tribal Health Care Research Project (THCRP) in Karnataka

The institute conducts outreach clinical research programmes with public health orientation for tribal caste population.Tribal Health Care Research Project was initiated in the year 2014 and THCRP team has reached out to 37,160 tribal population and 14,066 patients were treated through house hold survey and medical camps were conducted in 143 villages till date.

Ayurveda Mobile Health Care Project (Scheduled Caste Sub Plan)

The institute conducts outreach clinical research programmes with public health orientation for Scheduled Caste population and was initiated in the year 2015. SCSP team has reached out to 43,287 population and 23,129 patients were treated in selected 36 villages through 952 tours. The following projects have been taken up under this

✅ Cross sectional survey to determine the prevalence of Non-communicable Diseases) and their risk factor among Scheduled Tribes in selected states across Indiaunder Tribal Health Care Research Programme (THCRP)

✅ Evaluation of efficacy and tolerability of select Ayurveda formulations in moderate Iron Deficiency Anemia – A randomized controlled trial under Tribal Health Care Research Programme (THCRP)

✅ Cross sectional survey to determine the prevalence of NCDs and their risk factors among scheduled castes across India under Ayurveda Mobile Health Care Project- SCSP (Scheduled Caste Sub Plan)

✅ A randomized placebo controlled trail of Ayush SR in perceived stress under Ayurveda Mobile Health Care Project- SCSP (Scheduled Caste Sub Plan)